[brandonmenc]

Type 2 diabetes cannot be reversed - it can only be managed.

Pre-diabetes can be reversed but once you have diabetes, it's permanent - until we figure out how to regenerate beta cells in the pancreas.

[didgeoridoo]

Medically-supervised fasting has been shown to reverse T2D, even in patients who have been on insulin for decades. Beta cells seem to be able to regenerate themselves: https://insulinresistance.org/index.php/jir/article/view/31/...

[brandonmenc]

Reverse diabetes, or just get people off of insulin?

Can someone who has had their diabetes "reversed" via fasting then get normal glucose responses after eating sugar?

The N=1 study you cited states that the subject still needs to take Metformin. i.e., he still has diabetes.

[brandonmenc]

Downvote me all you want, but someone taking Metformin STILL HAS DIABETES.

[astura]

Bariatric surgery has been shown to reverse diabetes.

http://care.diabetesjournals.org/content/34/Supplement_2/S36...

>It has been over 10 years since the resolution of type 2 diabetes was observed as an additional outcome of surgical treatment of morbid obesity. Moreover, it has been shown unequivocally that diabetes-related morbidity and mortality have declined significantly postoperatively, and this improvement in diabetes control is long lasting.

[brandonmenc]

This falls under "figuring out how to regenerate beta cells."