[esm]

Interestingly, this gets into the territory of the Framingham Heart Study, a long-running, prospective cohort study of cardiovascular disease risk.

The data are mixed. One analysis, for example, showed that "Type A behavior" was not correlated with CVD[1]. Another showed that increased tension was associated with heart disease[2]. You can find plenty of other papers on the subject as well.

Job-related stress is a particularly interesting aspect of this. Conceptually, it makes sense that demanding work would increase cortisol levels and lead to CVD, but a number of studies don't bear this out after correcting for smoking, exercise, and so on. However, one could argue that job-stress leads to higher rates of smoking, drinking, etc., which makes the interpretation harder. It may also be that stress at work is not the only factor, and that the combination of high stress plus low control over one's work is substantially worse than one or the other alone.[3]

It is a bit unsatisfying to not have a clear answer, but I think the issue is more nuanced than I would have assumed.

[1]https://www.ncbi.nlm.nih.gov/pubmed/665654 [2]https://www.ncbi.nlm.nih.gov/pubmed/16204425 [3]https://www.ahajournals.org/doi/full/10.1161/jaha.117.008073