You can statically link to LGPL libraries so long as you also provide your program in "object form" so that the user can re-link their program with a different version of guile.
Surprised to see Guile weighing in at 2mb - my experience with it on Linux was a much larger install. What makes the Linux packages so much larger out of curiosity? I profiled it at more like 50-80mb when I compiled it a couple of months ago.