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by ekianjo 2775 days ago
> Yes, but patients always consent to be randomized to the possibility of being treated with placebo.

This is false as a blanket statement. For specific categories like Cancer treatments, nobody is given placebo in Phase III for example, because their life/survival is at stake. For such clinical trials you prove the efficacy by comparing with the typical survival in other studies/other treatments (overall survival chart) like this: https://media.revlimid.com/wp-content/uploads/mm-hcp-overall...

1 comments

Right, more correctly I should have said:

Yes, but in trial where patients may receive placebo, the patients always consent to be randomized to the possibility of being treated with placebo.