If you are interested in learning more the general name for this drug (outside of the US) is ARX-04.
The maker has some data that compares it to Fentanyl [1]. Their numbering states that is closer to 100x, and crosses the blood brain barrier in around 6 minutes.
Interesting. I'm a bit confused about slide 6, which says that it has a theraputic index which is 100 times better than fentanyl. It cites the reference [1], which indeed has those numbers in it, but the full table there is:
ED50 LD50 Theaputic Index
Fentanyl 0.01 3.1 277
Sufentanil 0.007 18 26716
The therapeutic index is the ratio of LD50:ED50.
This clearly makes no sense, someone must have moved a decimal point, and got a number which is wrong by a factor 10.
EDIT: Ok, it seems that it is indeed an error in the cited paper, but the typo is for the ED50 number. In the original source[2] it's given as 0.00071, which agrees with the "10 times stronger than fentanyl" claim in the original article, and gives the correct theraputic index.
EDIT: Ok, it seems that it is indeed an error in the cited paper, but the typo is for the ED50 number. In the original source[2] it's given as 0.00071, which agrees with the "10 times stronger than fentanyl" claim in the original article, and gives the correct theraputic index.
[1] https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1440-1681.... [2] https://twitter.com/davidjuurlink/status/859227636400349184?...