[joshuacc]

Ha! Sorry about the confusion. I meant to type Minion, not Myriad.

I definitely agree that you should be designing with the majority in mind. But if you set up good fallbacks then you can get 30% with fantastic type and 70% with quite decent type.

I don't tend to do "pixel perfect" design. I prefer designing in the browser, but can see how the traditional approach would make things difficult.

[tdupree]

Right on :) I've been tasked lately with a lot of "this needs to look the same for everyone on every platform" pixel perfect sort of stuff, so I have had to deal with getting everything the same and haven't had a lot of leeway. If you have the opportunity to give that 30% fantastic typography, and the other 70% still has a great experience, I'm definitely cool with that.