[adinb]

Which makes sense in light of the recent research implying crippled metabolomics in mitochondria (altered/less efficient ATP production chain)

[cpncrunch]

No, recent studies have debunked Myhill's claims. See for example the Tomas et al review I posted in another comment here.

[adinb]

Not going off of Myhill at all. More talking with Dr. Klimas and most of the important ME papers in the last year.

[cpncrunch]

Link to a review that contradicts Tomas?

[adinb]

I'm not sure exactly which point you're shooting for, my point is more about the provable altered metabolomics discovered over the past year and a half by Dr. Ian Lipkin, et al. Example paper from this summer:: https://www.nature.com/articles/s41598-018-28477-9

[cpncrunch]

It looks like that article you quote is referencing "Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients". However if you look at Tomas' study, they were not able to replicate that study:

"Contrary to previous literature [15, 28] which suggested that abnormalities in PBMC ATP levels may be caused by glycolysis, results from the glycolysis stress test showed that glycolysis in CFS patients does not differ significantly from that of the non-disease cohort. "

So you need to be careful that the studies you're looking at have actually been replicated. In this case it wasn't replicated.