[mcbain]

Unfortunately, no.

That is the case with GCCs __builtin functions. With a few exceptions, intrinsics are basically macros for inline asm that the compiler can reason about.

If on x86-64 you use a _mm256* intrinsic and compile without AVX support you just get a compile error, not a pair of equivalent SSE instructions.

[rurban]

Even worse. You mostly get run-time errors when the built machine supported that feature, your machine doesn't, and the features aren't separated into multiversioning or loading different shared libs.