[Bogdanp]

Having used pure pip + virtualenv{,wrapper}, pip-tools + virtualenv, poetry and Pipenv for medium to large applications, I'm going to be sticking to pip-tools for the time being for apps. Poetry is fine, but pip-tools is faster and there's less to learn. Pipenv is unbearably slow for large applications and often buggy.

For libraries, I've been using Poetry for molten[1] and pure setuptools for dramatiq[2] and, at least for my needs, pure setuptools seems to be the way to go.

[1]: https://github.com/Bogdanp/molten

[2]: https://github.com/Bogdanp/dramatiq

[epage]

The problem I ran into with pip-tools (and I assume pipenv has this) is that the lock files are platform and python-version specific (evaluates all of the conditionals for the given platform) when I do a lot of stuff cross-platform.