|
|
|
|
|
|
by simen
2803 days ago
|
|
|
> "Increase GABA" - I thought oral GABA supplements do not cross the blood-brain barrier? Oral GABA doesn't cross the BBB in appreciable concentrations, but I assume they mean increase GABA neurotransmission, which can be done with any number of ligands that do cross into the brain. Probably not benzos, since long-term usage increases the risk of Alzheimer's (and cognitive impairment is an effect even in healthy individuals). But perhaps something like baclofen (chloro-phenyl-GABA) which was tested in a rat model here: https://www.ncbi.nlm.nih.gov/pubmed/29133125 |
|
|