An important detail in many of these studies (I'm not sure if it applies here, it's not clear on the paper)
is that mice High Fat Diet isn't high fat as in keto.
Keto is: high fat, almost zero carbs, many vegetables (normal to low calories and low insulin peaks)
HFD in mice studies is: we put more fat in the normal mice food to give them more calories so they get fat (very high calories with insulin cycles)
An important detail in many of these studies (I'm not sure if it applies here, it's not clear on the paper) is that mice High Fat Diet isn't high fat as in keto.
Keto is: high fat, almost zero carbs, many vegetables (normal to low calories and low insulin peaks)
HFD in mice studies is: we put more fat in the normal mice food to give them more calories so they get fat (very high calories with insulin cycles)