I'd rather not trust my life to "probably". If there was some damage to the hull or a cargo door that could lead to failure, it's under more stress and is more of a hazard as the altitude increases.
Engine power is a fraction of weight. Even at full thrust (which is rarely used in commercial service, even for takeoff), the engines are only capable of 0.25g or so.
A famous example of this is American Airlines flight 96 (1972): https://en.wikipedia.org/wiki/American_Airlines_Flight_96