[epmaybe]

I don't know if I'd call them localised experiences per say, as I feel it minimizes what patients experience. I've probably done that to commenters here in the past regarding depression and pharmaceuticals.

However, I largely agree with what you are saying, everyone is going to have different reactions to these medicines. They're all "dirty" (note that SSRIs are far more specific in effects than previous generations of antidepressants) in terms of the vast number of effects neurotransmitters have in our brain, so it's understandable that they wouldn't work the same for everyone.