Democrats use state rights to protect scientifically and economically sound policies when there is an obvious bad faith actions on the part of the Federal Government.
That’s a bad argument to make, only because conservatives believe that their state’s rights issues also stem from scientifically and economically sound policy.
No they don't. Their arguments are based around different interpretations of the constitution and protection of various ill-defined "freedoms" (freedom from religious persecution, freedom of choice etc.)
They happily do not include science in their political calculus.