[fabricexpert]

You can reach ketosis without fasting, it's worrying that both this article and it's source are not really clear on the methodology.

This the actual source:

"Here we report that β-HB promotes vascular cell quiescence, which significantly inhibits both stress-induced premature senescence and replicative senescence through p53-independent mechanisms.

Further, we identify heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) as a direct binding target of β-HB. β-HB binding to hnRNP A1 markedly enhances hnRNP A1 binding with Octamer-binding transcriptional factor (Oct) 4 mRNA, which stabilizes Oct4 mRNA and Oct4 expression. Oct4 increases Lamin B1, a key factor against DNA damage-induced senescence.

Finally, fasting and intraperitoneal injection of β-HB upregulate Oct4 and Lamin B1 in both vascular smooth muscle and endothelial cells in mice in vivo. We conclude that β-HB exerts anti-aging effects in vascular cells by upregulating an hnRNP A1-induced Oct4-mediated Lamin B1 pathway."

https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)3...

[Amygaz]

I read it too, and there is absolutely nothing new. Pick any protein network database, and all these actors are already linked. Basically, you could have written the same conclusion without sacrificing any mice.