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Yes, I worked remotely for both US and Canadian clients. Dealing with Quebec clients is a pain (need to file their sales tax, _in french_), otherwise it's been a smooth sailing. Just remember that you're a contractor, not an employee.

[sridca]

I'm from Quebec as well. Do you work directly for a client, or through a consultancy?

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Directly. One of my friends is holed up in Yukon working via a website similar to upwork. Seems to work for him although these kind of sites generally get bad rep on HN.