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by clankfan 2867 days ago
Psychosis resulting from meth withdrawal has always suggested to me that it is an under-connected problem because presumably what happens during withdrawal is widespread "disconnection" resulting from a large decrease in synaptic sensitivity (caused by a flood of neurotransmitter, meth) and a steep drop in neurotransmitter activity once the meth is gone.
1 comments

Stimulants shred the cells' mitochondria. Psychosis is a metabolic problem.