[oarsinsync]

That's about as trivial as compiling a custom kernel. Possibly less so, as compiling a kernel in Debian/Ubuntu takes less than 10 commands.

[mirimir]

Yes. I used the latest version of Debian stable available from the VPS host. In most cases, I just upgraded to buster and installed headers. On one VPS that I didn't want to upgrade, I built a custom kernel. The WireGuard build didn't take long, and was no hassle.