[Kalium]

I suspect you may mean that ICBMs with atomic weapons are existential threats. Most people would not regard an ICBM equipped with a conventional explosive warhead as being capable of annihilating humanity.

If anything, this should hint at the difficulty of forecasting. The full impacts of some technologies cannot be understood without also knowing what they synergize with.

[dekhn]

Yes, I mean ICBMs with atomic warheads.

That said, ICBMs with (conventional) thermobaric warhead could do a lot of damage- you could effectively take out a medium sized country's industrial sector in an hour.