They give the impression of the building being alive. And therefore your presence is potentially a threat that it will deal with and you'll be trapped for an eternity in an endless maze of reconfiguring hallways and dead ends.
Well I wasn't feeling this way but now I am... Seriously though I prefer the more organic feel. I don't really like square hallways and I wouldn't mind being in a rounder room. though it would need to take into the actual requirements of the rooms. A shop class needs both a lot of space and square enough walls/floor plan that they can fit in equipment without a ton of wasted space.
Weird, I had the opposite feeling, it looked comfortable and organic and natural to me. Maybe it depends on how regularly you get out into and appreciate nature.