[ridgeguy]

RoI may go beyond financial measures for some of us.

I'd invest even if the only yield is longer/better life rather than $.

More $ - not terribly important beyond a threshold.

Longer/better life - yeah, that's important no matter how much money I have.

[darawk]

Sure. But in order to understand this, think about your own personal finances. Not theoretical super-rich you - current actual you. Are you going to buy the stock of a pharmaceutical company that develops drugs that aren't profitable? I'm not. And what that means is that companies developing unprofitable drugs don't get funding.