[adrice727]

I read "Lost Connections" by Johann Hari[1] a couple weeks ago. He spends much of the first section on the research and history of antidepressants. One particularly interesting thing is that drugs that decrease serotonin levels are just as effective as those that increase serotonin. The same goes for drugs that alter levels of dopamine. It seems that a great majority of the effectiveness of antidepressants comes from the placebo effect, and the remainder is somewhat of a mystery. Also, doesn't cure imply something that is permanent and not just a temporary measure?

[1] https://www.theguardian.com/books/2018/jan/17/lost-connectio...

[llamaz]

I don't know much about human biology, but if the relationship between dopamine/seratonin and depression/anxiety is more non-linear than linear, then the fact that both increasing and decreasing dopamine/seratonin is effective can make perfect sense. This sort of relationship - where small changes shift an equllibrium and result in a qualitative change - are common in nature and a forteriori human physiology.