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by aaffttoonn 2944 days ago
Thanks for the feedback on the AMH language. We are always trying to find the best way to simplify the science. In regards to AMH, great question! AMH is known by the clinical community as the best marker for ovarian reserve. I know everyone doesn't have access to peer reviewed journals so here are a few quotes: Podfigurna et al 2017: "AMH level is recognized to be the one of the most reliable markers of ovarian reserve [60–65]. AMH is mainly produced by granulosa cells of the pre-antral and small antral follicles and AMH levels decline with age. AMH level, especially in comparison with FSH level, was considered to be very stable across the menstrual cycle, but more recent studies have shown a slight decrease in AMH concentrations in the luteal phase [56,57]. Moreover, unlike other tests of ovarian reserve, such as AFC and FSH, it has sufficient specificity and sensitivity [58]. AMH concentration correlates with age and AFC" // Leader and Baker 2014:"Hundreds of clinical studies confirm that adding serum AMH testing to a complete ovarian assessment provides a powerful tool to help provide better healthcare for women. The benefits of this testing can optimize fertility treatments; help lead to earlier diagnoses of PCOS, POI, POF, and certain autoimmune conditions; provide the opportunity for better planning for procreation and menopause; and allow for better medical decision-making by monitoring ovarian damage from exposures to medical or surgical therapies. Although challenges with variability in AMH results make the provided practical steps a prerequisite for appropriate interpretation of the testing, the clinical benefits of testing more than justify this additional effort." We have a great post on the science behind ovarian reserve testing here: https://modernfertility.com/blog/ovarianreserve/
1 comments

> We are always trying to find the best way to simplify the science.

Please don't.

Just be honest and try to actually solve the problem of explaining science in layman terms rather than doing away with the explanations and complexity altogether.