I hadn't done any scientific studies, just had read about it and decided to give it a try on my phone. It made a difference for me, so I wanted to make something for chrome since as a dev I spend most of my day on there.
I'd say it's worth a try at least to see if you see a difference. It's strange browsing without color, and when you use grayscale and go back to color it almost feels overwhelming.
Here are some articles though that go into it more: