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by tpm 2953 days ago
Apparently not that horrible, with 25mg of psilocybin: Treatment with psilocybin produced rapid and sustained antidepressant effects. Decreased depressive symptoms were observed in all 19 patients at 1-week post-treatment and 47% met criteria for response at 5 weeks. https://www.nature.com/articles/s41598-017-13282-7