[drdaeman]

> But why

Legacy setups from previous decades, laziness, automated installers written by others (so they play by different rules), semi-broken packages with messed-up dependency graphs that require manual treatment. The comic is, of course, exaggerating - or at least I hope no one have things gone that bad.

> every sane programmer uses ... pip in a virtualenvwrapper environment

Check out Pipenv <https://docs.pipenv.org/> - you may like it. It aims to make things saner that bare pip+virtualenv{,wrapper}, and IMHO it really does.