[kazinator]

The study isn't denying that there are effects.

> neither persistent nor serious effects from MSG ingestion

Effects don't have to be serious or persistent for them to be a nuisance enough to avoid!

I don't need six hours of a mild headache/nausea, thanks.

[bpicolo]

This context was important on the study:

> large doses of MSG given without food

[kazinator]

That could describe the situation when you're drinking MSG-laced soup. The liquid will race ahead of the solids ingredients like noodles and get absorbed first.

If MSG is sprinked onto something dry, like some types of snack food, which is then washed down with a drink, it could also be absorbed fast.

[tptacek]

This is first-principles message board hypothesizing. In fact, there's enormous incentive in academic science to actually demonstrate a reliable adverse MSG effect, and there has been for decades. Why has no reputable study done so? Is it really your argument that no food scientist has ever thought of the study design questions you're alluding to here?