Experimentation does not necessarily mean killing. (Though lab animals are usually euthanized once they are no longer "useful".)
But we're not talking about experimenting on 15 million volunteer humans. We're talking about experimenting on 15 million animals incapable of consent. That figure should be equally morally repugnant to you.
it is problematic. but 1) we 're mostly talking about mice - higher animals are a lot more regulated and 2) the best we can do is to improve experiment registration and reporting in order to avoid all the redundant work and improve progress , saving those animals. The discussion about replicability, study size and chasing p-values is relevant.
But we're not talking about experimenting on 15 million volunteer humans. We're talking about experimenting on 15 million animals incapable of consent. That figure should be equally morally repugnant to you.