[joe_the_user]

Hypothesis testing is "soul" of science.

What's impossible is thinking that just the output of a single experiment gives hypothesis certainty, or a fixed probability of a hypothesis or anything fully quantified.

You're alway going to have the context of reality. Not only will you have the null hypothesis you'll competing hypotheses to explain the given data.

But the point of science isn't blinding constructing experiments but instead forming something you think might be true and doing enough careful experiments to convince yourself and others in the context of our overall understanding of the world that the hypothesis is true. Common sense, Occam's Razor, the traditions of a given field and so-forth go into this.