[kmm]

I don't see how insulin leading to fat storage changes anything about the caloric balance. Insulin promotes fat storage because it's a signal glucose is available in the blood, and the body prefers glucose over fat. So much so that making new fat is pretty rare, your fat stores are usually made directly from your diet. But if you replaced those sugars with the same calories worth of fat, you'd just burn that fat, and at the end of the day, exactly the same amount of fat will have been stored.

That's like saying that calling `fsync` will make your files bigger because it promotes data storage. It might store some data earlier, but the end balance is the same.

[tacon]

While calories in vs calories out always holds, that doesn't explain the entire system. It is like saying Bill Gates is rich because he makes a lot of money. Well, duh. A theory of weight balance in humans needs to account for the sudden weight gain when hormones change as we age, in women especially. If something changes homeostatis, the fact that we can still restrict calories by fighting the new urge to eat is not much comfort.