[Chriky]

The way a Rubix cube works, the center tiles never move.

[umanwizard]

Why is that relevant to the question?

All it means is that you only have to look at them once, at the beginning of the solve.

But since computers have memory, that’s true for all the tiles.

[BurningFrog]

It's not per solve, it's "per cube".

That is, the top center is always the same color, for every solve.

[umanwizard]

Presumably after you mix up the cube, you can put it in the machine in any orientation, can’t you?