[epmaybe]

Yeah...nucleolin is pretty ubiquitously expressed in most cells. How specific is their aptamer (antibody?) ?

Additionally, this is a similar idea to chemo embolization procedures (something I know is done in the US for some liver metastasis, but is being investigated for other solid tumors), where a catheter delivers a massive dose of chemotherapy at an artery supplying the tumor, and then closes that artery off.

[tyingq]

Maybe something like glucose consumption? PET scans are pretty good, though still subject to false positives, for tumors. Especially around cells like you find in the mouth.