[tyu100]

Right, so since a common problem with anti-depressants are the varied side effects of different classes (insomnia, weight loss/gain, sexual dysfunction, etc.. and etc..) a big part of going on an anti-depressant is you and your doctor finding a drug and a dose that shows both efficacy and a tolerable side effect profile.

This study generalizes this process by discussing both efficacy (how well the drug helps with depression) and the tolerability of the treatment, as measured by how long people tend to stay on the drug (the site is down right now so I forget the actual term used). Once the paper is accessible again have a look at some of the graphs that chart both of these measures. Generally, the drugs in the upper-right quadrants are better, showing both good efficacy and tolerability.