[keyboardhitter]

I do not know why you're being downvoted. I feel your comment added to the discussion of the article

I also learned recently that sebum production -- and inflammation -- are both complex mechanisms. As with most regulatory systems I wouldn't be surprised if they were linked in some way. But obviously I don't want to claim this in some hand-wavy way. Can you share any reading material you found when exploring the topic?

I have recently started Spironolactone for various PCOS symptoms, including acne vulgaris, so it's of interest to me

[platinumrad]

Probably the formatting. I didn't downvote and found it interesting but had a bit of trouble reading the blob of text. I find that capitalization is really helpful when reading longer paragraphs, especially if many of the sentences themselves are compound.

[the_cat_kittles]

thanks. i was honestly surprised to be down-voted, maybe that explains it a bit.