[pippy]

The existence of sickle cell and cystic fibrosis means we have a moral obligation to use it, and prevent these horrible diseases.

We have ethical justification to use genetic manipulation to enhance lives. By not doing so you're sentencing people to a life of suffering.

[ben_w]

CF yes, if I correctly understand that it evolved to help us deal with cholera — which we have now pretty much solved.

Sickle cell would be immortal to fix prior to fixing malaria, because the gene that causes sickle cell when you have two copies also makes malaria much less dangerous with one copy.