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by the_af 3073 days ago
Wasn't there a similar argument (linked to here on HN a few years ago) against early screenings for prostate cancer using highly sensitive techniques?

If I remember correctly, the argument went like this: early screening may detect some forms of prostate cancer which, given the estimated natural lifespan of the patient, would have failed to kill/discomfort him before he died of other causes. But once it's been detected, the recommendation will be to treat the cancer; and treatment has a chance to cause discomfort (such as impotence) right now. So in effect, early detection of some forms of prostate cancer may negatively impact the quality of life of patients who would have otherwise lived a normal life without noticing the cancer.

I might be remembering some details incorrectly.

1 comments

https://academic.oup.com/jnci/article/101/19/1325/1073822

"Given the considerable time that has passed since PSA screening began, most of this excess incidence must represent overdiagnosis."