[taloft]

Sorry, but the chances of this are minuscule. However, there is a chance and it depends on their mental state, how much they've flown the simulator, what types of maneuvers they've practiced and how closely it matches to the actual aircraft. One thing that would vastly improve your odds is getting ahold of a flight instructor or another pilot via the radio.

One thing a pilot is never allowed to do, is give up (no matter what); and neither should you if caught in a survival scenario.

If this is a real concern for you, check out something like the AOPA Pinch Hitter's Course, which can teach someone to land an airplane during an emergency with only minimal flight training. See http://www.avweb.com/news/safety/183024-1.html

If your question is more along the lines of "does a simulator make an acceptable substitute for an aircraft?", the answer must be no. Simulators are really only useful as a supplement to actual flight experience and training.