Have you tried dropping the dose and interleaving with acetomenophin? I have been hearing recently that's an increasingly popular strategy, sharing the load between the kidneys and liver.
Because they work in different ways, that's what I'm fond of doing for myself and my children. Start with ibuprofen, then try a table of acetaminophen a couple of hours later.
If it's a really bad headache, start with one of each.
If it's a really bad headache, start with one of each.