[subroutine]

I don't think we necessarily need to know the function of the genes in order to create a participant matching paradigm that is better than what is being employed currently. For example we can get a more precise snapshot of ancestry using sequencing than simply relying on self-reported 'race'. Also I don't think it needs to be a perfect match; simply stating that controls matched case participants within X percent ancestry would be a useful statistic to report in the methods.