No need to be flipped because the Keybee arrangement starts from the center of the keyboard. So it is optimized for left and right handed at the same time.
I thought you did not understand but rethinking I think Marco is mostly right, actually.
If I am a right hand user, the right part of my keyboard is covered by my hand, and is easier to be used. I've seen this in keyboard which don't have any keys on a 1/4th circle on the bottom right of the screen.
If I am a left hand user, the left part of my keyboard is covered by my hand and is easier to be used. But the left part of the keyboard has less important keys than the right part.
Essentially, a mirror of the keyboard would be more optimal for left hand users. Although the issue is less important than on say QWERTY. Because the amount of space on the outer rings (most strain) is still the same for left and right hand users. And that's Marco's point.
The amount of space your fingers can move back is smaller than the amount of space they can reach up. Going back puts more strain on the fingers. (Anecdotal experience.) (EDIT: and the arm, as well.)
Typed on Keybee.