[delbel]

THC inhibits the GABA neurotransmitter. GABA is responsible for the "calmness" factor in the brain. Low levels of GABA cause anxiety, paranoia, etc. Certain strains have different terpenes profiles. Terepenes are responsible for the aroma of the flower. Some terpenes change the way THC is absorbed, including preventing the inhibition of the THC GABA effect, which is why terpenes are also responsible for the aromatherapy of a strain. Strains have different terpene profiles based on their genetic makeup.

[danenania]

That's really interesting. Do you know of any sources that list these sorts of properties for strains (and that are reliable/empirical)? I presume the tags on sites like Leafly that mark a strain 'calming' or 'good for depression' are anecdotal and not based in chemistry?

[smcnally]

Some empirical effects reasearch from the NIH: https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabi...

[wolco]

I think you need to go deeper because each batch can give a different profile so the strains only provide a guideline.

What you could do is map the smell to the terpene profile.

http://maryjanesdiary.com/terpenes/