No, stopping ad blockers would be trivial today if the ad distributors let their JavaScript and ads be distributed from the same domain as page content. As long as the ads come from clearly identifiable domains, there is a good chance at stopping them.
Assembly never stopped anti-virus suites. Where there's a will, there will always be a way.
Without adblock, the majority of web users would be FURIOUS with websites and they'd demand legislative action. Advertisers should shut up and pray they don't poke the hornets nest.