There are several options which will depend on your background and country of citizenship, among others, such as the E-1, E-2, H-1B, O-1, and visas specific to certain countries of citizenship but many of these require the establishment of an employer/employee relationship, which can be a stumbling block. That is why, if possible, the E-1 and E-2 (and O-1) are oftentimes the best options for founders/entrepreneurs.