[kyleslattery]

With my Droid, I regularly have to reboot to get GPS to work, and I've had the issue on all 3 of the Droids I've had (replaced due to other issues).

[jokermatt999]

Have you tried just toggling the GPS settings? I occasionally have issues with it, but toggling the setting has always worked for me.

[kyleslattery]

Yes, that sometimes works, but there are a lot of times where I need to do a restart of the phone too.