[strebler]

Based on the paper, I think there is sufficient evidence for "mice who have increases in sEH expression in Müller glia cells" to consider they stop taking Omega3. As I understand it, that's some sort of genetic condition?

This paper is not very clear for the layman and even if it was, it's very common to find completely contradicting results for similar studies in the biological sciences. Biology is not easy!

Anecdotally, there is a fair amount of papers related to Lutein being beneficial to T1DM and retinopathy but the best I could get out of my endocrinologist was "it doesn't look like it will do harm and could help, so go ahead".

The best I could say is to further investigate sEH in humans (which I will be doing also), speak with your doctor and make the best informed decision you can for yourself. Don't forget that you're not a mouse.

My primary questions will be 1) how does soluble Epoxide Hydrolase relate to T1DM? and 2) what is the likeliness that either T1DM patients in general (or me specifically) may have elevated sEM expression?