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Tl;dr No

The field of probability was invented by largely French philosophers wanting to understand the math behind casino games. Casino games are nothing more (or less) than pure math. The 'unethical' part of casino comes from operators extracting too large of an edge. Obviously, the operator needs to make something to get paid to run the game, but the 'house edge' can be around 10%.

When thinking about gambling being ethical or not, IMO the important question is the price of the risk, not the mechanic of money traded for risk. Money for risk is very common (think insurance for example). Nobody would argue insurance is unethical. But if a home owner policy cost the price of the house annually, people would consider that unethical.