[klmr]

> NGS on the other side is more or less a gradual development.

While true that’s not really relevant. What’s relevant is that it has completely revolutionised biomedical research. And although CRISPR has the potential of doing the same, it’s just telling that RNA-seq (and related technologies) have become so routine that they’ve effectively spawned new fields of research. Together with WGS (and preceded by microarrays), the new sequencing technologies have led to a revolution of how science is done: because most of the science here is done at a computer. CRISPR, by contrast, is “merely” a new molecular biology tool. A very powerful, for sure, and one that opens up completely new avenues of research. But it doesn’t fundamentally change the way we do science. NGS has.