[trendia]

Your last quote is the opposite of what the paper says. The authors write that insulin resistance is not sufficient to cause AD and that other things are required:

> Therefore, T2DM and obesity may contribute to, i.e., serve as cofactors of AD but by themselves are probably not sufficient to cause AD. Moreover, the findings in the T2DM/obesity model indicate the unlikelihood [emphasis here] that brain insulin resistance is sufficient to cause AD and that additional significant abnormalities, such as ongoing DNA damage and mitochondrial dysfunction, are required.