Also, every few months take a few minutes and make sure that you really are backing up what you need.
I had a client a few weeks ago that had a drive failure. We went to restore from his offsite backup copy and found that some of the files he needed weren't being backed up. A quick review of the backup job would have caught this.
Amen! You only know how painful this is if you've something very important. Not-backing-up cost me, shoot I don't know, at least $4,000 once, and probably more than that.
Also, answer this question: If your home burns down, will your backup still work? I like to have one or two hard copies, and one cloud copy of the most important things.