| Small point first… eating the same amount but exercising more equals a caloric deficit in the same way that exercising the same amount but eating less does. I am not following your point about muscles specifically but I think we can let that go provided you agree that being in a caloric deficit needn’t mean you eat fewer calories. That is all I was trying to say regarding exercise. Second point… confusion is not the same as controversy. Even though people might be confused how the mechanisms and pathways work doesn’t mean they are controversial. Hormones dictate weight gain and weight loss. See pregnancy or puberty or menopause. (You even mentioned Thyroidism.) It’s not controversial. Calling it pseudoscience seems over the top. See the green house effect (first argued in 1824) for an analog. Third point… my claims pertain to the biology not to the marketing behind certain diets. I don’t believe that the atkins diet is ketogenic… nor do I think the Voedingscentrum is correct in saying the diet has a ‘varied and full-bodied eating pattern’, but I also don’t care. As you say… it is hype. But if your counter-examples have no explanatory power, then they are just as worthless. More on this below. In the very least don’t equate the hormone hypothesis with an endorsement for Atkins. Fourth point… I concede that my rhetoric is not iron clad. Since science is a process and certainty is always a question… it is hard to ever win an argument about this stuff… as Katan points out doing double-blind studies is near impossible so that makes claims in nutrition science doubly fraught. Having admitted that… I stand by my statement that the hormone hypothesis is not controversial. Yes the lipid hypothesis had sway in American culture in the mid 20th century but evidence to back it up was never produced. If any controversy existed, I would say it lay with the lipid hypothesis not with the endocrine one. As to the bonfides for sugar induced obesity I would point to Jean Anthelme Brilliat-Savarin (writing in 1825), Alfred Moore (writing in 1860), John Harvey (writing in 1861) , and William Banting (1863). Their accounts were accepted by medical schools in the US and the UK, with varied levels of understanding, through to the 20th century… where Thomas Cleave and John Yudkin were their antecedents. Does that make my 200 year claim iron clad? Not really but I think it is good enough for arguments sake. Last point… you haven’t made a case for an alternative to the hormone hypothesis. The links you included don’t do it. Your examples don’t do it. The Katan article doesn’t say that low carb doesn’t work… let alone provide an alternative mechanism for losing weight. As I wrote above… caloric reduction is a associated with instances of losing weight… but it doesnt CAUSE you to lose weight. Hormones do. |